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Download scientific diagram | – Cnidoscolus quercifolius plant. from publication: Análise Química e Bromatológica da Forragem da Faveleira (Cnidoscolus. PDF | Objective: To evaluate the chemical components of active extract from Cnidoscolus quercifolius root bark and its cytotoxic potential. The Cnidoscolus quercifolius (Pohl) popularly known as “favela” or “faveleira” is a forager that is part of the native species from the caatinga.

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In the agar diffusion method, the extracts showed activity against strains of Staphylococcus and E. Therefore, the root bark extract of Cnidoscolus quercifolius has a possibility of use for anticarcinogenic therapies. The importance of medicinal plants in solving the health problems of the world is gaining more and more attention.

Van De Meent, K. Standing out among these auspicious outcomes are the antioxidant effects, the bactericidal and fungicidal potential, and the inhibitory effect against the acetylcholinesterase enzyme in two extracts tested, which showed no significant difference when compared with the reference drug.

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For Holetz et al. There was no statistically significant difference between the LME and RBME with the reference drug Eserinewhich represents a new source of bioactive compounds with potential as acetylcholinesterase inhibitor Figure 2. The in qusrcifolius antioxidant activity of the extracts was determined using the 1,1-diphenylpicrylhydrazyl DPPH method, as previously reported by Brand-Williams et al.

It is a rustic plant of rapid growth, belonging to the Euphorbiaceae family [ 13 ] and Cnidoscolus genus [ 14 ]. The results suggest that the substances present in faveleira Cnidoscolus quercifolius root bark extract have a cytotoxic potential against several tumor lines, showing a broader antitumour potential, and querclfolius addition no adverse to healthy cells. Studies conducted by Almeida and Amorim [ 36 ] showed that the methanolic extract of the root of C. However, Conforti et ncidoscolus.

After performing the test to evaluate the antioxidant potential of extracts of C. It is important to note that this method only assists in optimizing querifolius selection and does not eliminate, under any circumstance, the in vivo tests [ 24 ].

The semiarid region of the Brazilian Northeast is known for hosting a number of native species that are under systematic exploitation in recent years, without any sustainable management, which ultimately causes the extinction of some species, thus unleashing a rural exodus.


View at Google Scholar A. In many cases, the procedures of modern medicine and popular medicine are supplemental and constitute an effective form of primary health care, which may supplement the treatment usually employed in the lower income population. The determination queecifolius the Minimum Inhibitory Concentration of Fungi MIC-f was obtained with a stereoscope, verifying the lower concentration of samples capable of inhibiting the growth of the microorganism, after 5 days quuercifolius incubation.

TLC evaluated inhibition of acetylcholinesterase enzyme AChEin accordance with the methodology described by Ellman et al. None, Conflict of Interest: Evidence-Based Complementary and Alternative Medicine.

To evaluate the chemical components of active extract from Cnidoscolus quercifolius root bark and its cytotoxic potential against several tumor strains. Ahmad and Beg [ 44 ] believe that the antimicrobial effect of vegetal extracts is largely due to the presence of flavonoids in their composition, thus corroborating the results found for the C.

Due to this increased interest, research on plants of medicinal importance is growing phenomenally at the cnisoscolus level. Then they performed a serial dilution of 2, at 4.

By agar diffusion method, the LME and the RBME showed similar activity by inhibiting the growth of Enterococcus faeciumEnterococcus faecalisStaphylococcus epidermidisand Pseudomonas aeruginosawhile the RME inhibited only the strain of Staphylococcus epidermidis. Several authors call attention to the direct dependency on this environmental resource by the populations living out of quercifoliux activities within the biome [ 910 ].

Spreading across an area of approximately thousand square cndoscolus, the caatinga, an exclusively Brazilian biome, is also one of the most endangered areas in the planet. It stands out for its extraordinary drought resistance and medicinal properties. Subscribe to Table of Contents Alerts. This is an open access article distributed under the Creative Commons Attribution Licensewhich permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

This difference in the presence and absence of certain chemical compounds of plant species may be related to factors such as age of the plant and the time of collection [ 31 ].

It was the start quercifopius a series of cultural intermixes that blended the knowledge brought in by the colonizers, the slaves, and the natives. This study did not detect alkaloids in any of the C. Almeida [ 43 ] performed an antimicrobial assay with strains of bacteria and fungi using hydroalcoholic extract of the leaves of C.


Peixoto Sobrinho et al. View at Google Scholar L.

Cnidoscolus quercifolius – Wikiwand

The World Health Organization WHO has recognized and recommended the dissemination of traditional knowledge and use of phytotherapic medicines. View cnidoscoluz Google Scholar I. The United States and Germany rank among the biggest consumers of natural products from Brazil. View at Google Scholar S. The lethality assay against Artemia sp.

Related articles Cnidoscolus quercifolius Pohl. View at Google Scholar C. Preliminary phytochemical analysis of C. In performing the inhibition test of fungal growth, it was observed that the LME showed inhibition against Lasiodiplodia theobromae LF11, L.

The present study, of crude methanolic extracts of Cnidoscolus quercifolius Pohl, has shown promising results in all tests performed. In the analysis of the leaves of C. Corroborating this, Kutchan [ 33 ] reports that the secondary metabolites have a direct relationship with plants and the environment in which they live; therefore, their synthesis is often affected by environmental conditions.

Despite the negative presence of alkaloids in the faveleira extracts tested, the plant presented satisfactory activity of enzyme inhibition, when compared with the reference substance, raising the possibility that new untested substances may act on the inhibition of AChE.

Man has long been using plants to promote health, in the belief that they carry beneficial substances for a healthy existence. View at Google Scholar M. Indexed in Science Citation Index Expanded. In the evaluation of toxicity of methanolic extracts of C. Thus, the antioxidant therapies used in a large number of illnesses related to the generation of free radicals, such as cancer, aging, atherosclerosis, ischemia, inflammation, and neurodegenerative diseases, seem to be promising [ 35 ].

The improvement of the conditions of oxidative stress by plants has been associated with phenolic compounds such as flavonoids and other polyphenols.

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